Program

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Monday 2 July 2012
NEXT GENERATION SEQUENCING & BIOINFORMATICS

8:15 a.m. - 9:00 a.m.             Registration

9:00 a.m. - 9:05 a.m.             Welcome & introduction
                                                  
Dr Nicholas Hamilton
                                                  Institute for Molecular Bioscience
                                                  The University of Queensland

9:05 a.m. - 9:45 a.m.             Next-generation sequencing: an overview of technologies and applications
                                                   Mr Matthew Tinning
                                                   Next-Generation Sequencing Manager
                                                   Australian Genome Research Facility Ltd

9:45 a.m. - 10:30 a.m.           Assembling next generation data
                                                   Dr Torsten Seemann
                                                   Victorian Bioinformatics Consortium
                                                   Monash University

10:30 a.m. - 11:00 a.m.         Morning tea

11:00 a.m. - 11:45 a.m.        Short-read mapping
                                                   Mr John Pearson
                                                   Queensland Centre for Medical Genomics
                                                   Institute for Molecular Bioscience, The Unviersity of Queensland

11:45 a.m. - 12:30 p.m.        Mutation detection in massively parallel sequencing data
                                                   Dr Ann-Marie Patch
                                                   Queensland Centre for Medical Genomics
                                                   Institute for Molecular Bioscience, The University of Queensland

12:30 p.m. - 1:30 p.m.           Lunch

1:30 p.m. - 2:00 p.m.             Transcriptomics 101
                                                  Dr Nicole Cloonan
                                                  Queensland Centre for Medical Genomics
                                                  Institute for Molecular Bioscience, The University of Queensland

2:00 p.m. - 2:45 p.m.              RNA-seq analysis pipelines
                                                   Dr Alicia Oshlack
                                                   Murdoch Childrens Research Institute, Melbourne

2:45 p.m. - 3:15 p.m.             Afternoon tea

3:15 p.m. - 4:00 p.m.             Differential expresion analysis of RNA-seq read counts
                                                   Professor Gordon Smyth
                                                   Bioinformatics Division
                                                   Walter and Eliza Hall Institute of Medical Research

4:00 p.m. - 4:45 p.m.              Metagenomics - characterising the composition and function of natural microbial communities
                                                   Dr Lutz Krause
                                                   Queensland Institute of Medical Research
                                                   The University of Queensland

5:00 p.m. till late                    Welcoming barbeque 
                                                  Sponored by SGI

Tuesday 3 July 2012
NEXT GENERATION SEQUENCING & BIOINFORMATICS

9:00 a.m. - 9:45 a.m.             ChiP-seq and epigenetics
                                                   Dr Alicia Oshlack
                                                   Murdoch Childrens Research Institute, Melbourne

9:45 a.m. - 10:15 a.m.           Infrastructure for genomics: workflows and visualisation
                                                   A/Professor Andrew Lonie
                                                   Life Sciences Computation Centre, VLSCI
                                                   The University of Melbourne
                                                   and
                                                   Dr Michael Pheasant
                                                   Genome Research Computing
                                                  The University of Queensland

10:15 a.m. - 10:45 a.m.        Morning tea

10:45 a.m. 11:15 a.m.           The future of genome sequencing technology
                                                   Mr David Miller
                                                   Queensland Centre for Medical Genomics
                                                   Institute for Molecular Bioscience, The University of Queensland

11:15 a.m. - 12:15 p.m.         Panel discussion

12:15 p.m. - 1:30 p.m.           Lunch

12:30 p.m. - 1:30 p.m.           Workshop - Introduction to the genomics virtual laboratory
                                                   A/Professor Andrew Lonie & Dr Michael Pheasant
                                                   3.141 Multi-media room, QBP

NEXT GENERATION SEQUENCE ANALYSIS

1:30 p.m. - 2:00 p.m.             NGS sequence analysis 101
                                                  Dr Timothy Bailey
                                                   Institute for Molecular Bioscience, The University of Queensland

2:00 p.m. - 2:45 p.m.            Word-based approaches to discover transcription factor binding motifs in
                                                  full-size ChIP-seq datasets
                                                  Professor Jacques van-Helden
                                                   Lab. Technological Advances for Genomics and Clinics
                                                   Université d'Aix-Marseille, France

2:45 p.m. - 3:15 p.m.             Afternoon tea

3:15 p.m. - 4:00 p.m.             Understanding genetic regulation in the era of massively parallel
                                                  sequening: how many sites should a transcription factor bind?
                                                   Professor Jacques van-Helden
                                                   Lab. Technological Advances for Genomics and Clinics
                                                   Université d'Aix-Marseille, France

4:00 p.m. - 4:45 p.m.             Understanding transcription with NGS - a biologist's perspective
                                                   Dr Michael Tallack
                                                   Mater Medical Research Institute, South Brisbane

Wednesday 4 July 2012
NEXT GENERATION SEQUENCE ANALYSIS

9:00 a.m. - 9:45 a.m.             Machine learning in anger
                                                  Dr Stefan Maetschke
                                                  Institute for Molecular Bioscience, The University of Queensland

9:45 a.m. - 10:15 a.m.          To trim or not to trim? A closer look at next-gen sequencing data and errors
                                                  Dr Michael Imelfort
                                                  Advanced Water Management Centre, The University of Queensland

10:15 a.m. - 11:00 a.m.         Morning tea

11:00 a.m. - 11:45 a.m.         ARS-seq: high-resolution mapping and mutational scanning of autonomously
                                                   replicating sequences
                                                   Dr Uri Keich
                                                   School of Mathematics and Statistics
                                                   The University of Sydney

11:45 a.m. - 12:30 p.m.         Probablistic data integration: putting sequence in context
                                                   Dr Mikael Bodén
                                                   School of Chemistry & Molecular Biosciences, The University of Queensland

** FREE WEDNESDAY AFTERNOON **

Thursday 5 July 2012
SYSTEMS BIOLOGY

9:00 a.m. - 10:00 a.m.           Introduction to systems biology
                                                   Professor Eberhard Voit
                                                   David D. Flanagan Chair
                                                   Georgia Research Alliance Eminent Scholar in Systems Biology
                                                   Georgia Institute of Technology, Georgia, USA

10:00 a.m. - 10:30 a.m.         Morning Tea

10:30 a.m. - 11:00 a.m.         Essential graph theory for biologists
                                                   Dr Nicholas Hamilton
                                                   Institute for Molecular Bioscience, The University of Queensland

11:00 a.m. - 12:00 p.m.         Overview of network methods in systems biology
                                                   Dr Daniel Hurley
                                                   Research Fellow, Faculty of Medical and Health Sciences
                                                   The University of Auckland, NZ

12:00 p.m. - 1:00 p.m.           Lunch

1:00 p.m. - 2:00 p.m.             Pathway analysis
                                                  Professor Eberhard Voit
                                                  David D. Flanagan Chair
                                                  Georgia Research Alliance Eminent Scholar in Systems Biology
                                                  Georgia Institute of Technology, Georgia, USA

2:00 p.m. - 3:00 p.m.             Constraint-based reconstruction and analysis of metabolic and regulatory networks
                                                  Professor Lars Nielsen
                                                  Australian Institute for Bioengineering and Nanotechnology
                                                  The University of Queensland

3:00 p.m. - 3:30 p.m.             Afternoon tea

3:30 p.m. - 4:15 p.m.             An introduction to the use of ontology in computational and molecular biology
                                                  Dr Melissa Davis
                                                  Institute for Molecular Bioscience, The University of Queensland

4:15 p.m. - 5:00 p.m.             Panel discussion

Friday 6 Juy 2012
ECOLOGY AND POPULATIONS

9:00 a.m. - 9:15 a.m.             Introduction

9:15 a.m. - 9:45 a.m.             Biophysical modeling and network analysis for exploring spatial patterns in marine
                                                  population connectivity
                                                  Dr Eric Treml
                                                  Department of Zoology
                                                  University of Melbourne

9:45 a.m. - 10:15 a.m.          Modelling the ecological implications of complex dispersal networks
                                                  Dr Michael Bode
                                                  School of Botany
                                                  University of Melbourne

10:15 a.m. - 10:45 a.m.        Managing food webs using Bayesian networks
                                                  Dr Eve McDonald-Madden
                                                  ARC Centre of Excellence for Environmental Decisions
                                                  The University of Queensland

10:45 a.m. - 11:15 a.m.         Morning tea

11:15 a.m. - 11:45 a.m.         Modelling the extinction risk of genetically structured turtle populations
                                                   Dr Peter Baxter
                                                   Centre for Applications in Natural Resource Mathematics
                                                   School of Mathematics and Physics
                                                   The University of Queensland

12:00 p.m. - 1:00 p.m.           How can mathematics help save the planet?
                                                   Professor Hugh Possingham
                                                   ARC Centre of Excellence for Environmental Decisions
                                                   The University of Queensland

1:00 p.m. - 2:00 p.m.              Lunch

2:00 p.m. - 2:30 p.m.              Searching for needles in haystacks
                                                   A/Professor Michael McCarthy
                                                   ARC Centre of Excellence for Environmental Decisions
                                                   The University of Melbourne

2:30 p.m. - 3:00 p.m.              How artificial intelligence techniques can help protect diversity: the
                                                   use of Markov decision processes
                                                   Dr Iadine Chadès
                                                   CSIRO Ecosystems Sciences, Queensland

3:00 p.m. - 3:30 p.m.              Afternoon tea

3:30 p.m. - 4:15 p.m              Panel discussion

4:15 p.m. - 4:30 p.m.            Recognition of student travel awardees & close of 2012 Winter School

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